Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 351
Gene Symbol: APP
APP
P05067 amyloid beta precursor protein Enzyme modulator 485 0.422 0.846 4.7E-02 0.500 None 0.994 159 3 1993 2020
Entrez Id: 627
Gene Symbol: BDNF
BDNF
P23560 brain derived neurotrophic factor Signaling 992 0.345 0.923 0.66 0.100 None 1.000 65 4 2005 2020
Entrez Id: 43
Gene Symbol: ACHE
ACHE
P22303 acetylcholinesterase (Cartwright blood group) Enzyme 418 0.445 0.885 1.00 0.400 None 1.000 33 0 2005 2020
Entrez Id: 5663
Gene Symbol: PSEN1
PSEN1
P49768 presenilin 1 Enzyme 369 0.469 0.846 0.97 0.500 None 0.966 29 3 2002 2020
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
P01584 interleukin 1 beta 1801 0.276 0.962 0.13 0.400 None 0.960 25 0 2008 2020
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.100 None 1.000 19 0 2007 2020
Entrez Id: 2932
Gene Symbol: GSK3B
GSK3B
P49841 glycogen synthase kinase 3 beta Kinase 393 0.430 0.846 0.96 0.090 None 1.000 9 0 2017 2020
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
Q16236 nuclear factor, erythroid 2 like 2 Enzyme 823 0.357 0.885 3.6E-03 0.090 None 1.000 9 0 2016 2020
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.080 None 1.000 8 0 2014 2020
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
P03372 estrogen receptor 1 Nuclear receptor 1101 0.324 0.962 1.00 0.080 None 1.000 8 0 2017 2020
Entrez Id: 3060
Gene Symbol: HCRT
HCRT
O43612 hypocretin neuropeptide precursor 237 0.500 0.808 2.9E-02 0.080 None 1.000 8 0 2017 2020
Entrez Id: 8803
Gene Symbol: SUCLA2
SUCLA2
Q9P2R7 succinate-CoA ligase ADP-forming subunit beta Enzyme 136 0.566 0.654 2.3E-03 0.070 None 1.000 7 0 2013 2020
Entrez Id: 5879
Gene Symbol: RAC1
RAC1
P63000 Rac family small GTPase 1 Enzyme modulator 415 0.429 0.962 0.76 0.060 None 1.000 6 0 2018 2020
Entrez Id: 2551
Gene Symbol: GABPA
GABPA
Q06546 GA binding protein transcription factor subunit alpha Transcription factor 632 0.379 0.885 1.00 0.050 None 1.000 5 0 2017 2020
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.050 None 1.000 5 0 2015 2020
Entrez Id: 857
Gene Symbol: CAV1
CAV1
Q03135 caveolin 1 Enzyme modulator 633 0.388 0.885 8.3E-03 0.040 None 1.000 4 0 2017 2020
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
P00441 superoxide dismutase 1 Enzyme 689 0.379 0.962 0.18 0.040 None 1.000 4 0 2011 2020
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
O00206 toll like receptor 4 1174 0.321 0.962 4.6E-09 0.140 None 1.000 4 0 2017 2020
Entrez Id: 834
Gene Symbol: CASP1
CASP1
P29466 caspase 1 Enzyme 444 0.413 0.885 3.5E-05 0.040 None 1.000 4 0 2017 2020
Entrez Id: 5524
Gene Symbol: PTPA
PTPA
Q15257 protein phosphatase 2 phosphatase activator Enzyme modulator 245 0.480 0.846 0.99 0.040 None 1.000 4 0 2013 2020
Entrez Id: 551
Gene Symbol: AVP
AVP
P01185 arginine vasopressin Signaling 454 0.437 0.846 7.4E-02 0.320 None 1.000 3 0 2001 2020
Entrez Id: 7442
Gene Symbol: TRPV1
TRPV1
Q8NER1 transient receptor potential cation channel subfamily V member 1 Ion channel 404 0.446 0.885 1.0E-16 0.030 None 1.000 3 0 2018 2020
Entrez Id: 183
Gene Symbol: AGT
AGT
P01019 angiotensinogen Enzyme modulator 765 0.367 0.923 5.0E-08 0.030 None 1.000 3 0 2017 2020
Entrez Id: 7054
Gene Symbol: TH
TH
P07101 tyrosine hydroxylase 321 0.462 0.885 1.7E-06 0.030 None 1.000 3 0 2017 2020
Entrez Id: 3350
Gene Symbol: HTR1A
HTR1A
P08908 5-hydroxytryptamine receptor 1A G-protein coupled receptor 229 0.522 0.846 0.20 0.320 None 1.000 3 0 2003 2020